1picasso100euros.com

Non-profit raffle. Buy a ticket for 100 euros for a chance to win a Picasso valued at 1 million euros. All proceeds go to Fondation Recherche Alzheimer, the leading organisation in France dedicated to research on Alzheimer's disease.

This is pretty incredible. There are 120,000 tickets, so chances you win aren’t super high, but that means the Opera Gallery gets its million for the painting and then 11 million goes to Alzheimer’s research. Hard to think of a better way to donate than this.